Posted by tecknohed on October 20, 2007, at 15:17:25
In reply to Re: Remeron - just trashed it!, posted by sdb on October 19, 2007, at 13:54:19
> I don't think Remeron is a good med to treat anxiety primarily this because it increases noradrenaline at higher dosages. It is indeed very sedating especially in the first days, regardless of the dosage (!) and the sex-drive can be big for many persons. I know that a depressed post heart stroke patient did well on it for some weeks. Personally I took extremely low dosages and I used it as a sleep med during an emotional shock period.
>
> warm regards
>
> sdbThanx for your input sdb!
You know, since stopping Remeron the most bizzare thing has happened. I've actually been feeling better! Admittedly, I have doubled my clonazepam from 1.5mg to 3mg over the last 2 weeks, but it seems that as blood levels of the Remeron get lower I feel better! Perhapse a small dose (7.5mg) would have suited me better.
But I still think I'd be overly anxious whatever the dose if I didn't have my clonazepam.
Of course blood levels of the drug will keep dropping by the day but I'm suprised my mood hasn't dropped yet (I've been off Remeron a whole week now).
Noradrenalin is a strange one though. For example, I find lofepramine, an NRI tricyclic (which is metabolized into desipramine) to be great for anticipatory anxiety ('butterflies', diarrhoea, etc) though at the same time it can aggrivate my general & social anxiety. I had a similar experience with reboxetine (another NRI). In fact, at one time my social phobia was so bad I was virtually agoraphobic, yet after 3 weeks on lofepramine I was able to not only leave the house but started college too! (though I still couldn't talk to anyone there 'socially').
Oddly, I've read from a few sources which report that Remeron may not be a dual action drug at all & may only effect noradrenalin, though I find this hard to beleive as it certainly 'felt' serotonergic to me. It felt very SSRI-like. Remeron definitely seems to worsen my anticipatory anxiety, which is exactly what the SSRIs do to me. Maybe it's serotonin effects are completely indirect(?).
Just my thoughts/experiences.
poster:tecknohed
thread:789137
URL: http://www.dr-bob.org/babble/20071019/msgs/790348.html