Posted by bleauberry on November 16, 2007, at 18:59:19
In reply to Buspar. Same as SSRIs? Induce mania??, posted by qbsbrown on November 15, 2007, at 16:11:29
I think it is impossible to predict. The actual mechanisms of these meds are not fully understood. Buspar and its metabolite have several varying mechanisms involving serotonin, norepinephrine, and dopamine. Over the years I have to say I have seen very few people who have gotten much benefit from buspar in anything.
If serotonin doesn't do it, and if benzodiazepines don't feel like the right thing, then that at least narrows down the field of focus a bit. Might want to think about blocking receptors instead with zyprexa or risperdal, or modulating the entire show with depakote, lamictal, or lithium.
Could be something real simple like the need for magnesium supplementation by either magnesium taurate or magnesium glycinate. A simple cheap way to get magnesium in you quick is to take a hot bath with 2 cups of epsom salts for about 15 minutes. Do it 2 to 3 times a week, though some people do it daily. The first time I tried it I did not feel anything after, but I noticed I slept unusually well that night and woke up unusually calm and in a slightly better mood. But I don't do well with pills or tablets. I seem to get more benefit absorbing it through the skin. It really takes weeks to months to get the magnesium stores back in shape, but you can still feel rapid improvement if that is the problem. Taurine is another one, very similar. Magnesium and/or taurine are crucial for controlling excess nervous system stimulation. While we all focus on heavy drugs, we tend to forget or downplay the basics of life which are extremely powerful influences on what we feel. Our bodies use and need a lot of magnesium, which is burned up fast in stressed states such as anxiety. Taurine can easily be deficient due to age, not enough in diet, genetic flaw in manufacture, or heavy metal burden. If you had multiple childhood vaccinations, multiple flu shots, and/or amalgam fillings, you have absorbed enough mercury to cause vulnerable people significant nervous system problems that look exactly like what you have described.
It could be your serotonin system and your benzo system are already working overtime at full capacity to indirectly calm/modulate things which magnesium or taurine should be doing instead.
One other thing to consider is that SSRIs do not make more serotonin. They only keep what little you have at the receptor synapse. You could try low doses of 5htp to see how you do with simply increasing serotonin universally throughout. You would not be the first person who did lousy on SSRIS but did good with 5htp or tryptophan. Serotonin reuptake inhibition versus serotonin production are not the same thing and not comparable, at least in my personal experience. SSRIs send me through the roof with anxiety and semi-mania mixed depression. 5htp doesn't.
Magnesium. Taurine. 5htp. Tryptophan. You might want to seriously look at these nervous system basics before introducing another drug. Your odds of having a deficiency in one of these is high. Your odds of having a deficiency in buspar or any other drug is zero.
A drug such as an antipsychotic or mood stabilizer might well be needed and justified. I'm just saying cover the most basic likely culprits first.
poster:bleauberry
thread:795303
URL: http://www.dr-bob.org/babble/20071115/msgs/795507.html