Posted by cumulative on November 18, 2007, at 19:30:24
In reply to Ketamine - I don't understand this, posted by deniseuk190466 on November 18, 2007, at 11:59:39
Neurotransmitter systems aren't really a unified system grouped by neurotransmitter across the brain -- the part of the brain and the system subtype, for instance, is quite important in this incredibly complex feedback mechanism, the brain. NMDA antagonists inhibit NMDA neurotranmission but they can potentiate AMPA, certainly tend to potentiate dopamine release, will definitely increase glutamate transmission during the rebound (hence concerns of excitotoxicity), can apparently evoke glutamatergic activity in the forebrain, probably as a function of dopaminergic activity ...
poster:cumulative
thread:795744
URL: http://www.dr-bob.org/babble/20071115/msgs/795823.html