Posted by linkadge on November 21, 2007, at 19:10:14
In reply to Re: New melatonergic antidepressant in USA trials, posted by mikez on November 21, 2007, at 14:54:46
It has moderate affinity for 5-ht2c, which might increase slow wave sleep. It might supress REM sleep which could account for AD effect.
The 5-ht2c antagonism could also account for antidepressant effect. I would also think such antagonism could possibly improve aspects of mania, or schizophrenia as well.
I have a feeling that it will work very well for some people but not well for others. It might work well as a Remeron type of drug with fewer side effects.
I don't think it will work for everbody though.
Linkadge
poster:linkadge
thread:795849
URL: http://www.dr-bob.org/babble/20071115/msgs/796436.html