Posted by linkadge on November 28, 2007, at 19:13:30
In reply to Re: Trivastal is an a2-adrenoreceptor antagonist?, posted by clipper40 on November 28, 2007, at 19:08:43
the a2 receptors are inhibitory autoreceptors.
They are invovled in homeostatic control over norepinephrine release. When you block these receptors it results in a *release* of norepinephrine. When you activate these receptors (like clonidine an alpha-2 agonist) you get less norepinephrine release.So drugs like mirtazapine, trivestal, or yohimbine, alpha-2 antagonists, will cause norepinephrine release.
Linkadge
poster:linkadge
thread:797501
URL: http://www.dr-bob.org/babble/20071125/msgs/797506.html