Posted by cumulative on November 29, 2007, at 22:26:28
In reply to Re: D1 stimulation question, for the psychopharm b » cumulative, posted by DStupid on November 29, 2007, at 22:16:43
Hey. Pramipexole (mirapex) and ropinirole (requip) are (somewhat expensive) non-ergoline DA agonists, that don't damage heart valves. These are both selective for D2 and D3 and there are some good threads here and some interesting literature elsewhere on the promising use of Mirapex for anhedonia, atypical depression, etc.
Probably not what I was looking for though, since they don't touch D1 much. Bromocriptine, another non-ergoline, actually antagonizes it.
Trivastal is also not derived from ergot. Not prescribed in the U.S. however.
The appearance of the heart valve problems is quite disappointing, since pergolide might have been what I was looking for.
As to your second thing, this might prove an interesting link for you, in particular Frangible's post:
http://www.mindandmuscle.net/forum/index.php?showtopic=31375
poster:cumulative
thread:797696
URL: http://www.dr-bob.org/babble/20071125/msgs/797736.html