Posted by Darius2535 on December 6, 2007, at 11:25:10
Hi everyone,
I wanted to know who is currently on Marplan and what success and effects have they achieved on it?
I have treatment-resistant depression and social/anxiety phobia. Have tried all SSRI, etc. But the only only drug that finally worked was Nardil last year.
Within weeks as soon as reaching 60mg Nardil totally lifted my depression and all anxieties, felt free, invincable, open, honest, could talk to anyone, very emotional. I couldnt believe it. That something Finally worked. I felt cured.
However it also caused a state of Mania, daytime sedation, talkativeness, repeating my words, aggressiveness, plus of course a slew of other side effects all for which my doc and I were using various antidotes to calm. In the end, I was fired from my job and was involved in 2 car accidents. I fell back into lethargic ambivalent depression, and then upped the dose to 75mg, which only caused MAJOR appetite increase and weight gain, and no more of the good effects. So I gradually discontinued it, and worked to lose the weight. That was last February (2007).
Since then my doc has tried few other meds and combos, but we still come back to the fact that MAOIs are the only one i REALLY responded to. (By the way, tried that Emsam patch before the Nardil and it didnt work at all).
Most recently, after much thought, my doc and I decided to try PARNATE, hoping it might have some effects similar to Nardil with fewer side effects and Manic state, etc.. Well I started Parnate and slowly went all the way up to 60mg on it, waited weeks and weeks. NOTHING. Yea it was stimulating, just making me run around and look to eat and eat anything decadent and fattening. I gained 15 pounds in 1 month, and NO theraputic effects. So I slowly tapered off Parnate, and now Im just washing out until maybe starting Nardil again with a new game plan, or trying MARPLAN.
My doc wants me to start Marplan, before attempting another trial of Nardil, which was the only medication that worked on me really.
So I just wanted to get some information from people who are currently taking MARPLAN, and whether it is helping them, etc..
Thanks for reading.
Darius
poster:Darius2535
thread:799117
URL: http://www.dr-bob.org/babble/20071204/msgs/799117.html