Posted by linkadge on December 8, 2007, at 9:44:48
In reply to Re: Why is Seroquel so popular as a sleep aid? » linkadge, posted by clipper40 on December 8, 2007, at 3:27:47
>I'm wondering even more about its advantage(s). >It probably doesn't have the cardio effects that >the tricyclics have.
It doesn't have the same cardiac problems as the TCA's do, but it has been associated with cardiovascular problems of its own.
>It's probably one of the few things that those >on MAOIs can take for sleep but for everyone >else, it doesn't seem to have that much more to >offer than cheaper, and potentially safer, >alternatives.
It is possible that by blocking monoamine activity at certain receptors, it is reducing the insomnia induced by an MAOI overstimulating such receptors.
>Maybe it works well and is easily tolerated so >doctors have an easy time prescribing it. >Perhaps you're also right that it's an "in" drug >to take right now.
I personally found low dose TCA's to be more tollerable. Seroquel makes me depressed. The neuroleptics are often prescribed in dementia (which makes absolutely zero sence outside of the goal of behavioral control), but such use has waned somewhat after studies showing lack of cognitive improvement (deterioration), as well as increased risk for stroke, falls etc.
The use in elderly is just convienient. Its not that they're necessarily the best choice, but that they can achieve some desired effect.
I think its just a convenient drug that is used because it is *newer* and hence uncontiously assumed to be better (?)
If seroquel works and nothing safer works, and you're happy, there is probably little reason to change. I'd just be cautious of doctors using it in the one side fits all category.
Linkadge
poster:linkadge
thread:799280
URL: http://www.dr-bob.org/babble/20071204/msgs/799496.html