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Re: Wellbutrin: SR totally different than XL? » Dragon Black

Posted by zenhussy on December 10, 2007, at 17:40:05

In reply to Wellbutrin: SR totally different than XL?, posted by Dragon Black on December 6, 2007, at 16:53:11

>>>I'm now on day 8 with the SR version, 150 mg x 2/day. Maybe part of it is that I'm monitoring myself more, but I feel like I am on a DRUG. It's like being on a moderate dose of amphetamine minus the euphoria/pleasure aspect. I think overall I probably do feel better, but I also just feel weird. It's been a big help with focusing at work and getting stuff done. But there are also the annoying aspects of being on a stim, like just not feeling normal, focusing too much sometimes, stomach feeling weird, etc. <<<

the mechanisms of release of the active medication in WB SR and WB XL are different. they're designed to release the active ingredient at different rates. due to metabolic differences some ppl feel certain versions of a med. more readily than another version. personally the XL was the mildest in the stomach dept. versus the SR and older original WB (the 3-4x/daily one).

the SR was noticably activating along w/ the weird stomach feeling and lack of desire to eat. the XL didn't have as much appetite suppression as the SR nor quite the kick-in-the-stomach feeling as the SR.

>>>Strongly anorectic! Can't believe how strong, have to remind myself to eat, calories are way down. Don't remember noticing this on XL (except to the extent that my self-medicating via eating due to depression largely stopped). Also, sex drive has dropped to almost zero. XL was fairly prosexual, almost too much at times. In short, it feels like a totally different med to me. Started Buspar on the same day (I know, obscures the perception of the individual meds, but I was desperate, and never had any problem going on XL and knew what it felt like). So far haven't noticed anything. I think my anxiety is up from the Wellbutrin, though, so some sort of effect is sorely needed. Also on 1.5 grams of EPA/day.
Anyone have a similar experience or know what the deal is? Shouldn't XL and SR "feel" the same?<<<

in theory they 'should' feel the same but due to how they're released and absorbed in the body they can differ widely for each perosn.

have personally found higher dose buspar to be very effective along w/ combo of wellbutrin xl and wellbutrin sr against long term depression and raging anxiety. has taken a long time w/ pdoc to arrive at this current cocktail that alleviates more symptoms than the annoying side effects that come along for the ride.

hope you can ride out the SR long enough to see if your body can adjust to it.

how's day 12 treating you?

 

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