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Re: Update w/ Questions MAOI, Bupropion... » sonic_gb

Posted by jedi on December 12, 2007, at 22:14:57

In reply to Update w/ Questions MAOI, Bupropion..., posted by sonic_gb on December 10, 2007, at 14:46:30

Hi Sonic,
I can't put my hands on the literature right now, but I have taken Nardil at 90mg and bupropion at 300mg simultaneously. Elisabeth, a very intelligent ex-poster on the board, gave me the idea. It is totally contraindicated and I have had PDOCS who said it would kill me, but I'm still here. I'll look for the reference. The negetive references will far outnumber the positive ones.

After you get Nardil up to it's affective dosage, you will find it will blow MOC away for both social anxiety and atypical depression. Nardil is the bomb. You may have a period of euphoria when the med first starts to take effect. This will go away, so don't misinterpret it for poop-out. Patients that are in it just to chase the nardil euphoria, won't be in the race very long.

I'm on 2mg of clonazepam for augmentation of social anxiety. I've been off clonazepam a few times and it does not seem to make a difference in my atypical depression. We are all a unique bunch. I take a small dosage of Seroquel(25 to 50mg) for the Nardil induced insomnia. It works great for this and I have had no tolerance issues after at least six months.

Good Luck Sonic,
Jedi


> Hello All,
>
> I hope I can draw on some of the collective wisdom here. Summary: I was admitted last Thursday for inpatient care for severe depression anxiety and insomnia. Meds were Wellbutrin SR 150mg 3x/day, Clonazepam, Oxazepam. The Wellbutrin only made the depression and anxiety worse. I was (and still am) dependant on the benzos, and I think they also made the depression worse.

>
> I finally saw the psychiatrist today for the first time. He agrees that Wellbutrin is totally wrong for me. I've been refusing to take it for 2 days anyways. He too me off it. Because of many, many previous treatment failures on just about every class of AD excpet for one short-lived glowing experience w/ Moclobemide, he has agreed to try me on Nardil dosage TBD. But since I was on Wellbutrin he says I need to wait two weeks to start. Is there any literature to the contrary? I can't find any specific studies.
>
> Also, if I DO have 2 wait 2 weeks, is there any reason I can't use Moclobemide in the meantime? There is no interaction between Moclobemide and Bupropion, but I'm not sure if there is a washout period between Moclobemide AND Nardil.
>
> Also, I'm tapering off the benzos, and tapering up Seroquel. Is this going to help with insomnia and daytime anxiety? What sort of dose range, and timing should I be looking for?
>
> Any overall comments on this treatment plan?
>
> I would really appreciate any help or advice that can be offerred here.
>
> Thanks,
>
> Sonic


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URL: http://www.dr-bob.org/babble/20071204/msgs/800468.html