Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: MAOIs and WEAK SRIs combination? » amigan

Posted by jedi on December 15, 2007, at 1:21:37

In reply to MAOIs and WEAK SRIs combination?, posted by amigan on December 14, 2007, at 23:55:49

Hi,
Trazodone in low dosage is often used as a sleep aid with Nardil. I have used it myself. I have also augmented Nardil with Nortriptyline, mostly as a sleep aid. There is some evidence that this type of TCA will help reduce the chance of a tyramine reaction with Nardil. I've taken nefazodone but don't know about any reaction with a MAOI.
Jedi


> Hello.
> I known that the combination of a MAOI with a potent serotonine reuptake inhibitor like all(?) SSRIs and certain TCAs like clomipramine can easily lead to a life-threatening, serotonine syndrome.
> But, would it be relatively safe to combine a MAOI with a low dose of a WEAK SRI, like trazodone, nefazodone or nortriptyline?
> Furthermore, some of these ADs are also blocking certain 5-HT receptors, which could be beneficial in preventing the development of a serotonine syndrome! (On the other hand, things might be more complicated with traz/nefazodone, as they are metabolized into mCPP which is a 5-HT agonist... but anyway, i refer them as an example)
>
> What do you think?
>


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:jedi thread:800899
URL: http://www.dr-bob.org/babble/20071213/msgs/800905.html