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Go for it! - 4WD

Posted by medjuggler on February 23, 2008, at 17:22:45

In reply to Re: Start Nardil at maximum dose without titrating? » phoenix1, posted by 4WD on February 23, 2008, at 16:11:50

>In a way, I'd like to go ahead and start at the full dose, deal with the side effects as best I can and get it over with. I'd also like it to kick in as quickly as possible. I'm in pretty bad shape right now.
>
> Marsha

Marsha, if thats the case then YES go for the full dose your pdoc recommended. But stay at that dose for at least 4 weeks. 'Normally' it kicks in after 3-4 weeks, though some wait ALOT longer. If after 5 weeks there is NO response at all then go to 60. Like I said before, the dosage-to-weight idea is a good one but its not set in stone.
If you start at the full dose then I believe this will speed up the MAO inhibiting process. Ideally you want a 90%+ inhibition for the antidepressant effect, though you should feel it's anxiolytic effects (from GABA) much sooner. I felt that from practically day one at 15mg.

GO FOR IT! GOOD LUCK!
mj


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