Posted by Quintal on March 14, 2008, at 10:39:31
In reply to Re: Aaaaaarrrrghhh I need to ejaculate, posted by squatlover on March 10, 2008, at 9:42:07
No, I haven't taken Periactin with an MAOI - it's only available on prescription where I live, but I would consider taking it with Nardil. My guess is that the manufacturers included a generic 'Do Not Use With MAOI'-type warning just to cover their backs. There are no serious (i.e. life-threatening/hypertensive crisis etc.) interactions reported between Periactin and Nardil though. The most I could find was a report of visual hallucinations and a decrease in the antidepressant effect of Nardil when combined with cyproheptadine:
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Interactions between your selected drugs
Minor Drug-Drug Interaction cyproheptadine and phenelzine (Minor Drug-Drug)
Cyproheptadine may antagonize the therapeutic effect of monoamine oxidase inhibitors (MAOIs). This interaction was reported in one patient treated with phenelzine for chronic depression. Another patient developed visual hallucinations following the addition of cyproheptadine to a stabilized regimen of phenelzine. Causality has not been definitely established. The mechanism is unknown but may be related to the antiserotonergic activity of cyproheptadine. Patients should be monitored for potentially diminished therapeutic response to MAOIs during coadministration with cyproheptadine. Discontinuation of cyproheptadine may be necessary if an interaction is suspected.
__________________________________________________I remember wanting to take diphenhydramine (Benadryl) with Parnate years ago, but was scared off by exactly the same type of warning in the package insert. Turns out many people here have been advised to try Benadryl for MAOI insomnia by their doctors. I've herad quite a few using it with no problems. I understand you being wary though - I wouldn't expect you to risk a major drug interaction just based on something you read on a message board, but I thik it does bear looking into a little further considering how annoying this side-effect is. Could you run it by your doctor?
Q
poster:Quintal
thread:816506
URL: http://www.dr-bob.org/babble/20080303/msgs/817862.html