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Re: serotonin syndrome

Posted by undopaminergic on April 12, 2008, at 20:40:50

In reply to serotonin syndrome, posted by David F on April 12, 2008, at 11:55:17

Serotonin toxicity can be treated with cyproheptadine tablets (about 12 mg), and in emergencies, with intravenous chlorpromazine (12-25 mg). Antagonism of 5-HT2A receptors is the relevant mechanism of action for this purpose.

The antidote should be administered without delay upon emergence of symptoms, as progression is sometimes rapid and unpredictable.


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