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Re: Inderal-vs-Pindolol

Posted by undopaminergic on April 17, 2008, at 21:49:02

In reply to Re: Inderal-vs-Pindolol, posted by Shadowplayers721 on April 17, 2008, at 9:51:18

Propranolol is very lipid soluble and crosses the blood-brain-barrier easily. Furthermore, it blocks beta2-adrenergic receptors in addition to the beta1-adrenoceptors relevant to hypertension.

Atenolol is much less likely to have depressive or other CNS effects. Unfortunately, it may also be less effective against tremor, but it may well be worth trying before propranolol.

There are many beta-blockers, and all have slightly different properties, especially as far as pharmacokinetics (metabolism, etc.) and other non-cardiovascular effects are concerned, as they were all developed for the purposes of reduction of blood pressure and heart rate.


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URL: http://www.dr-bob.org/babble/20080412/msgs/823923.html