Posted by Questionmark on April 27, 2008, at 2:42:33
In reply to Parnate Users-increase in Depression?, posted by orchidrare on April 21, 2008, at 10:30:12
That's strange. I experienced moments (periods?) of extreme depression when i was on Parnate, but they were totally of the excessively emotional, oversensitive, feeling-too-much nature. Incidentally Nardil has been by far the best antidepressant for me-- best drug period for all my issues in general.
> Hello There
>
> I am hoping someone might lend a little help with some side effects I am experiencing on Parnate. Your aid would be much appreciated.
>
> I have had dysthymia (double depression) since about 9. I am now in my 30's. I have tried the various ADs (SSRI's, TCA's, Effexor, Wellbutrin, etc.) medications with minimal success. I have now been put on Parnate, starting with 10mg per day increasing by 10mgs per week up to 40 mg per day. I have been on 40mgs per day for nine days.
>
> Within one hour on the first day I started taking (10mg) I developed weakness that saw me needing help to walk and tremendous fatigue. It seemed my head was also struggling with this weakness, if that makes sense. I have continued to increase the dose nonetheless. The weakness has improved enough to move unaided (though not enough to leave the house) but my voice is still weak and the 24-hour fatigue is still marked.
>
> It has also seemed to bring on a deep depression with absolutely no drive and motivation, none of which seems linked to the weakness which I had originally thought. It is as if I am a human-shaped balloon and all the air has been taken out leaving me heavy and unable to lift limb or whole body or mind. I have always struggled with lack of energy and wondering what is the point. But I have never experienced not caring about anything, which I have developed in the last few weeks. I just don't care.
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> I am persevering as the medication deserves it's chance to work and I want it to work. The doctor agrees with this. Will the weakness and fatigue subside? And the apathy? Has anyone else experienced an increase in depression on Parnate?
>
> Thanks for reading this.
>
>
poster:Questionmark
thread:824567
URL: http://www.dr-bob.org/babble/20080420/msgs/825758.html