Posted by undopaminergic on April 30, 2008, at 13:53:58
In reply to Re: A few Cyprenil (liquid selegiline citrate) ?s, posted by alucard on April 29, 2008, at 16:54:32
> >On a more disconcerting note: Discovery, who made the first liquid depreynyl citrate which is now off the market claims that selepryl and cyprenil are fakes and are just liquid selegiline hcl.
> I wrote the company that makes these meds and asked them about that and have not heard from them yet.
>
> bulldog2 & undopaminergic & everybody - I too read Discovery's claim that Cyprenil and Selepryl were actually just liquid selegiline HCl intentionally mislabeled as the citrate, and I read that BEFORE I ordered the Cyprenil. Here's my thoughts on it:
>
> First of all, as Discovery mentions on their website, they never actually made the liquid deprenyl citrate (LDC from now on) themselves, they contracted with a Mexican pharmaceutical company called Cyto-Pharma to make it for them. Apparently Discovery developed the PROCEDURE to make LDC, but then they licensed the use of that procedure to Cyto-Pharma so it could be made cheaply and then imported through Discovery.
>I don't think Cyto-Pharma was given the procedure for making selegiline, only for formulating the so-called "Liquid Deprenyl Citrate" (trade mark). At least according to:
http://www.imminst.org/forum/index.php?showtopic=303&st=0&p=2931&#entry2931Quotation of the relevant passage:
"The procedure to only formulate Liquid Deprenyl Citrate was given to Cyto Pharma, but not the procedure for manufacturing deprenyl. The procedure to manufacture deprenyl free base was given to another company in Mexico. The deprenyl free base was then provided to Cyto Pharma to formulate into Liquid Deprenyl Citrate."> > What is your liquid selegiline like? Is it an oily yellowish liquid, or does it seem more like water?
>
> undopaminergic - The Cyprenil I'm taking is a clear liquid the consistency of water that has a slightly bitter citric taste to it, so it's not the freebase.
>So you believe it's an aqueous solution of the citrate salt of selegiline?
Without further data, I would assume it's a solution of the hydrochloride, because no-one has (to my knowledge) ever reported the preparation of a citrate salt of selegiline. Therefore, the characteristics (melting point, solubility, stability, etc.) of such a compound are unknown.
Theoretically, the molecular weight of selegiline citrate would be 379.40. Therefore 2.03 mg of selegiline citrate would correspond to 1 mg of the freebase, or 1.19 mg of the hydrochloride. You would need to take this into account when determining the dosage.
poster:undopaminergic
thread:825078
URL: http://www.dr-bob.org/babble/20080430/msgs/826426.html