Posted by cumulative on May 7, 2008, at 18:32:44
In reply to Fast acting options for suicidal ideation?, posted by Racer on May 6, 2008, at 10:00:21
Your regimen is dopaminergic psychostimulants. This is what I, typically low-energy and lacking in volition/"spark/joie de vivre, respond to as well. Unfortunately the mood improvement from these tends to be a bit flighty, and in some users, following tolerance to most of the mood effect there is a sort of deadening feeling. Perhaps the prefrontal stimulation (which tends to sensitize) clamping down on limbic dopamine transmission. That is of course pure theory.
Anyway, memantine. Have you considered memantine?
This seems to have worked fantastically for some people here in regards to completely halting the tolerance to the stimulant mood improvement, as well as apparently having fairly significant antidepressive effects on its own.
poster:cumulative
thread:827471
URL: http://www.dr-bob.org/babble/20080430/msgs/827814.html