Posted by SLS on May 23, 2008, at 12:41:24
In reply to Re: Anyone had success with Moclobemide for anxiet, posted by Quintal on May 23, 2008, at 9:27:21
> No, it's not a very effective drug at all. It doesn't seem very wise to combine it with 600mg venlafaxine either, but let's hope your pdoc knows what he's doing. It tends to cause quite a bit of anxiety and agitation at first, so watch out for that. I can think of much better non-benzo anxiolytics than moclobemide.
I agree.
> I took 900mg for six months, and it was an absolute waste of time. Beyond the inital startup agitation/insomnia it didn't seem to do anything at all. I was taking it for social phobia.Some people go up to 1200mg, but that is usually after they had some sort of positive response at lower dosages. It seems that you can get a good response at as low as 300mg, but then you have to keep increasing the dosage to chase down the improvement as it is constantly fading.
Roche started a program in the US over ten years ago to try to get moclobemide approved for social anxiety / phobia. They dropped the project once clinical trials failed to show efficacy.
- Scott
poster:SLS
thread:830647
URL: http://www.dr-bob.org/babble/20080519/msgs/830702.html