Posted by jms600 on May 28, 2008, at 9:31:55
In reply to Re: The best Tricyclic for anxiety...., posted by linkadge on May 27, 2008, at 19:37:13
> I would think doxapin, elavil or clomipramine would be better than imipramine for GAD. These two have antagonist effect at 5-ht2a/c, 5-ht3 which imipramine does not have. I think imipramine is the most studied in this regard but that does not necessarily equate to efficacy.
>
> If sleep disturbance and/or GI problems are prominant, this might be another reason to choose elavil or doxapin which have antihistamine effects too.
>
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> Linkadge
Linkadge,You said that "These two have antagonist effect at 5-ht2a/c, 5-ht3" Which two were you referring to; Doxapin, Elavil or Clomipramine??
Surely Clomipramine must have some sort of antagonist effect at 5-ht2a/c and 5-ht3 due to it's anxiolytic effects??
Thanks
jms
poster:jms600
thread:831465
URL: http://www.dr-bob.org/babble/20080528/msgs/831616.html