Posted by bleauberry on May 28, 2008, at 15:19:52
In reply to Doxycycline and mood swings, posted by cactus on May 27, 2008, at 21:32:05
Doxycycline definitely affects the brain. No doubt about it. I felt it myself when on it a few weeks ago. 100mg/day for 3 weeks. The Marshall Protocol (an abstract pioneering treatment for FM and CFS based on resetting the immune system) uses minocycline, but for those who can't tolerate it doxycycline is mentioned. They warn though that doxyclince does affect the brain, where minocycline does not. They said that 200mg or higher of doxy can induce mild euphoria.
Anyway, I definitely had worsened depression on doxy. It is supposedly a rare side effect. Doc and pharmacist said all I might get is nausea, nothing psychiatric. Wrong. There was one day however when I swear I was in remission. I mean, I sat and watched a movie, thoroughly enjoyed it, laughed, talked, and just felt alive. It was awesome. But it was a one-day fluke.
The whole time on doxy I noticed I had more energy, more endurance, and it seemed like any chemical or food sensitivities I had just vanished away. It was pretty cool actually.
The darned worsened depression though. Dang. Oh, also, doxy gave me restless legs syndrome. Clear evidence it does something in the central nervous system. It also doubled the loudness of my ongoing tinnitus.
When I stopped doxy I went through a two day withdrawal period not unsimilar to withdrawing from cocaine, ritalin, or an antidepressant.
Doc wrote me a script for minocycline to replace doxy, saying it was tamer, but I was too gunshy to try it.
poster:bleauberry
thread:831517
URL: http://www.dr-bob.org/babble/20080528/msgs/831685.html