Posted by stargazer2 on June 3, 2008, at 22:20:01
In reply to Re: Nardil....'New' Nardil as good as Original?, posted by Treehugger on June 3, 2008, at 11:59:08
Marplan was discontinued in 1994 while I was on it and I was destabalized and it took years to find another med combination to help me, and even then it was not the same as my complete and total response to Nardil and Marplan. Marplan is now back, and I tried it last year without any success, and I believe it was reformulated too since that is how they make it more cheaply and by doing this render it a completely different med.
Why don't the stupid greedy drug compnaies know once the formula is changed, they are essentially sealing their fate and will never market the product successfully again. Small changes in psych meds can completely change the way the drug is absorbed, especially if they mess with the excipient ingredients, like they seem to all do.
When will they learn it is not just the active ingredients that count but also the way the ingredients are combined which greatly effects the absorbancy and half life.
Stupid scientists. I thought they had the science of drug availabilities well understood...they don't at least based on the reformualtion of nardil and more than likely Marplan.
I think there were (are) many more users of Nardil than Marplan that were left high and dry, although the changes in both formulas have greatly affected my recovery from a treatment resistent depression which only responded to MAO's as they were originally formulated.
Why mess with the effective formula, you will not achieve a home run after reformulating it. It may be cheaper to make but the users know the difference and will not tolerate the negative changes in the newer formualtions.
Big Greedy Pharma is all about $$$. I hope you have a relative with depression who is suffering too as a result of your cheaper methods to reformulate a once superior product.
make the real thing and you may find you will have a product that can beat out many of the newer, useless antidepressants. MAO's were the greatest until you got your greedy hands on them.
It's all about the money not the patients anymore, no ethics or altruism, just bloody greed.
Prove me otherwise and reproduce the real Nardil and Marplan again. bet it will never happen...you messed up the best treatment I ever had for depression. Too bad you never tested the reformulations on real patients, that would be too honest and meaningful. Just test it on normal, healthy patients, who have nothing to lose, except perhaps experience some nasty side effects, like I live with every day.
Testin on healthy subjects is a useless endeavor for a reformulated drug, I hope you go out of business for your less than scientific apprach to being as greedy as you possibly can.
can anyone forward this to Pfizer. They are such A$$HOLES, they shoud go out of business.
poster:stargazer2
thread:831601
URL: http://www.dr-bob.org/babble/20080528/msgs/832790.html