Posted by cactus on July 6, 2008, at 15:05:28
In reply to Re: Alcohol and Anti-depressants., posted by undopaminergic on July 6, 2008, at 9:07:15
*whereas Zoloft may slightly enhance them (additive serotoning and dopamine reuptake inhibition). Higher doses of Zoloft would be likely to block the effects of MDMA if taken prior to it, due to blockade of the serotonin transporter which is required for the serotonin-releasing effects of MDMA. On the other hand, if Zoloft is taken after MDMA, it may possibly prolong its effects somewhat. Zoloft and other serotonin reuptake inhibitors are also known to protect against the toxicity of MDMA to serotonergic neurons if taken before or soon enough after MDMA.*
True to a certain extent but I have seen it go both ways, I have seen SSRI's block the effects of MDMA or prolong it's effects. I have also seen it cause serotonin syndrome. I personally don't think it's a good idea to try because you don't know which way you will be effected.
poster:cactus
thread:838143
URL: http://www.dr-bob.org/babble/20080706/msgs/838455.html