Posted by West on July 22, 2008, at 18:38:23
This is the website of retired Australian Psychiatrist and Pharmacologist Dr Ken Gilman. He has experience in the research and publishing of clinical data and has some GROUNDBREAKING conclusions regarding the efficacy of currently marketed antidepressants. The website includes figures stating exact reuptake affinities for various drugs (like those for venlafaxine: 5HT:NE inhibition 200:1). From a personal perspective for example, I found it very helpful to discover that both SNRIs effexor and cymbalta have insubstantial effects on 5HT and NE to warrant a theraputic response, whilst a combination of sertraline + reboxetine/nortryptaline does - the catch being the lack of interest in marketing the combination of either of these drugs. Take a look:
http://www.psychotropical.com/dual_action_ads.shtml
main website:
poster:West
thread:841488
URL: http://www.dr-bob.org/babble/20080718/msgs/841488.html