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Re: (STAR-D*) helpful link for more info. » linkadge

Posted by Larry Hoover on August 3, 2008, at 21:10:07

In reply to Re: (STAR-D*) helpful link for more info., posted by linkadge on August 3, 2008, at 19:54:08

> I'd like them to follow remission rates and determine relapse rates.

This paper fully discusses those two issues: http://ajp.psychiatryonline.org/cgi/content/full/163/11/1905

I think an interesting finding is that full remission occurred about 50% of the time between treatment weeks 6 and 12, calling into question the findings of clinical trials of short duration. Very few even monitor for 12 weeks, and may thus miss successful treatment outcomes.

> Also, a placebo arm would be nice to sort out real from placebo response.
>

We've already discussed at some length why placebo could not have been part of this trial. STAR*D was a naturalistic study, and no practitioners employ placebo in their medical practise.

Lar

 

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poster:Larry Hoover thread:843960
URL: http://www.dr-bob.org/babble/20080727/msgs/844006.html