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Re: research » Jeroen

Posted by FrequentFryer on August 22, 2008, at 23:54:38

In reply to research, posted by Jeroen on August 22, 2008, at 9:44:32

> hi, its worth a try atleast im going to do this
> you have 2 option but i recommend the memantine 30 mg one because it can be that one has been studied. note both are medicine against alzheimer
>
> OPTION 1
>
> memantine... the nmda antagonist, that has been theorized to reverse or hold off tolerance to psychostimulants. It has been working brilliantly for two full months, in combination with modafinil and a fairly steady intake of caffeine...
>
>
> OPTION 2:
> As others have noticed, tolerance develops. It's my experience that selegiline helps reverse it, and that after approximately a week of selegiline (10 mg/day p.o.) abstinence from dopamine autoreceptor antagonists, a prominent stimulant response is again possible upon resuming the antagonist.
>
>
>
>

Thanks for that.. I have read that NMDA antagonists prevent tollerance and Memantine can be used to potentiate a number of drugs and prevent (or even reverse) alcohol, cocaine, opiate, and amphetamine tolerance.

It dosn't seem to interact with many other drugs either. But I dont know if it would help an MAOI or SSRI.

What drugs are you going to supplement it with?

D-Amphetamine used to fix all my problems but recently it just gives me insomnia.


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