Posted by Fra Angelico on September 21, 2008, at 4:32:13
In reply to Re: Brief immediate responses to meds?? - Advice Pls, posted by bleauberry on September 8, 2008, at 21:24:56
My theory is this: that the body is in a constant state of normalization and of attempting to restore the status quo. As with self-repair - healing - after a traumatic injury, there is a cogntive 'map' of some kind which tells the body just how it should be restored for normalcy and the status quo to be restored.
New medications may at first disturb the (depressive) status quo, allowing for the development of positive affect and well-being, but the normalization process perceives this change as an injury, and starts to restore or repair it, so reverting to the previous depressive state.
I have myself experienced wonderful - but very temporary - benefits from moclobemide - which quickly faded back into the status quo of dead-end dysthymia, and am now - sadly - experiencing the same thing again with phenelzine/"Nardil".
It is harder to see the good affect and liveliness go, than never to have experienced it at all.
poster:Fra Angelico
thread:850938
URL: http://www.dr-bob.org/babble/20080915/msgs/853206.html