Posted by Peter S. on September 22, 2008, at 18:27:25
In reply to Buprenorphine experiences » Peter S., posted by kingcolon on September 22, 2008, at 0:26:47
Thanks for the response. What side effects have you experienced? Did you have any problems getting your doctor to prescribe it for depression? I'm wondering if I can get my HMO pdoc to go for it.
Regards,
Peter
> Hi Peter,
> I split the dose in two or three times a day intervals. The studies on depression, as well as for pain, seem to use split doses even though for addiction maintenance, a single daily dose is generally used. I think the biologic half-life is very short in comparison to the pharmacologic half-life. I do notice some "slipping" of mood toward the end of the dosing interval (say 6-10 hrs). The antidepressant effects did not occur instantaneously with me (unlike what is reported by others)--it took about a week to max out. There were anxiolytic effects almost immediately however. The sense of well-being it gave as well as it's motivating and anti-anhedonic effects have been the best of any medication I've taken over 15 years.
> If others want to comment on their Sub experiences or add info on it, we should change the thread title since the original study was already referenced by undopaminergic.
poster:Peter S.
thread:831927
URL: http://www.dr-bob.org/babble/20080915/msgs/853492.html