Posted by linkadge on September 25, 2008, at 20:38:02
In reply to Re: Circadin - Lundbeck launches new melatnonin tablet » Bob, posted by Quintal on September 25, 2008, at 14:03:13
Melatonin is a powerful anxioxidant. It has sleep regulating effects and HPA axis regulating effects. It also increases the neuroprotective protein BCL-2 in hippocampal tissue.
Melatonin has antidepressant effects in the chronic mild stress model of depression in rats.
It can reverse the AD effect of SSRI's, but I would hesitate to call it depressogenic.
Linkadge
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