Re: Seroquel effects at very low doses » mav27

Posted by yxibow on October 21, 2008, at 2:42:35

In reply to Seroquel effects at very low doses, posted by mav27 on October 20, 2008, at 8:09:18

> Just wondering if 25mg of seroquel has any effect at all on dopamine and seratonin receptors or does it have no effect at all until higher doses ?
> I take just 25mg a night for sleep so i'm just curious if it does have any other effect at this tiny dose.
Seroquel has a wide dosing range typically to 800mg. At 25mg you're only getting the effects of an antihistamine / muscarinic receptors and possibly the slightest amount of serotonin if at all (some people believe it balances the sleep cycle). The dopamine Ki constant is so high at that point that you're getting close to nil.
Its a starting dose for taking Seroquel though for its intended (or off label purposes), at about the 100-200mg level you do start getting D2 effects.
-- Jay

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Seroquel effects at very low doses mav27 10/20/08
Re: Seroquel effects at very low doses Jeroen 10/20/08
Re: Seroquel effects at very low doses » mav27 yxibow 10/21/08
Re: Seroquel effects at very low doses greywolf 10/21/08
Re: Seroquel effects at very low doses Roslynn 10/21/08
Re: Seroquel effects at very low doses Phillipa 10/21/08
Re: Seroquel effects at very low doses » Roslynn yxibow 10/21/08
Re: Seroquel effects at very low doses Roslynn 10/21/08

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