Posted by yxibow on October 26, 2008, at 23:40:32
In reply to Re: one-off remeron dose-did i do something dangerous?, posted by g_g_g_unit on October 25, 2008, at 21:18:16
> > Probably nothing. If it's one-off I'm missing how it would activate you.
> >
> > -- Jay
>
> sorry, i guess i was still a little scrambled at the time i wrote that. i've been trialling 10mg of nortriptyline at night for the past 2 weeks and do feel some initial activation upon taking it, meaning i generally have to dose it around 6/7pm if i want to fall asleep by midnight. because i didn't want to exacerbate my insomnia that night i thought i'd skip the nortriptyline, but since i didn't have any benzos, i still needed a sleeping aid since i find lying awake drunk pretty unbearable. i know nortriptyline has a long half-life so i imagine there was still some in my system when i took the remeron and i just wanted to make sure it wasn't dangerous.
Curious -- usually the TCAs are neutral to sedating but everyone is different.If you were worried about the interaction, now I see -- the dose you took wouldn't have caused Serotonin Syndrome on a one-off, it basically has no properties there -- in fact its a debate how much it has at a high dose, though I believe it helped me that way at one point except for the weight issue.
It's best to clear your system of alcohol (i.e. wait the number of hours of alcohol that you've drunk, at least some of them anyhow) before embarking on your nighttime agents, even if they seem activating, are potential CNS depressants.
The only time I blacked out in my life that I can recall was with Trazodone and uncleared alcohol. Don't do this at home folks, please.
Amitriptyline is more dangerous with alcohol and dose in general -- I won't go into the reasons for obvious ideation, but just to warn people not to go there.
Insomnia is a problem for many people with depression including myself -- its gotten worse over the years, I've been through sleep medications, basically no benzo-related medication will work because I'm still on a (now lower) dose of Valium. So I'm left with Trazodone (thats a non starter I think now because of mCPP) and the TCAs.
Sometimes though one just has to go natural with sleep cycles, it can take weeks to correct your sleep pattern by going to bed at the same time each night, i.e. backpedaling until you reach an optimal time.
That hasn't worked for me yet but ultimately all sleep aids have their life cycle and its rinse and repeat :/.
-- Jay
poster:yxibow
thread:859188
URL: http://www.dr-bob.org/babble/20081016/msgs/859440.html