Posted by yxibow on November 11, 2008, at 0:44:54
In reply to Re: Trazodone vs. Seroquel, posted by desolationrower on November 10, 2008, at 17:05:16
Trazodone I find to be rather icky going to sleep because it makes me feel faint (do not mix with alcohol, it was my only blackout in my life I think, I had thought I had it all out of my system, alas), but its often prescribed. The main issue with it, if you are male is priapism risk. Its very low, but it is there. And then there's the theoretical mCPP metabolite, but that's probably more rare, which could cause a bit of psychosis.
Its one of those antidepressants that you can get tolerant to the sleep effect because well, people actually used to take it as an antidepressant. It does form 5HT blockades sort of like APs, probably not as strong.
Then there's the tricyclics, doxepin and amitriptyline in small dosages which can also promote sleep but the first dose usually knocks you off your *ss. That is if you're not used to sleep agents in the first place.
As for Seroquel, well 25mg has nearly no AP effect and some say it has a good sleep promotion, I don't see why there's a lot of danger in it -- it can also be one of those things that one eventually becomes accustomed to the antihistamine effect.
Basically all of these agents are being taken for an antihistamine or muscarinic effect.
As they say, your miles may vary
-- Jay
poster:yxibow
thread:862047
URL: http://www.dr-bob.org/babble/20081106/msgs/862223.html