Posted by NewQuestions on December 8, 2008, at 11:29:01
In reply to Strange shift in 5HT tolerances, posted by zzz7 on December 6, 2008, at 13:51:54
I can totally relate to this! I was on a relatively high dose of Zoloft for years, then experienced new side effects (mental fog, confusion, lethargy, muscle ache, apathy). The other SSRI's didn't work either--some made me more anxious, some made me more depressed! I tried many other drugs too (cymbalta, effexor, wellbutrin, TCA, MAOI) and they all had devastating side effects. Like you, I became hypersensitive to the drugs.
You may want to try lamictal, which does not work on the big three neurotransmitters (it helped me a little but affected my cognition too much), or stablon, which works on serotonin but in a different way. I have not tried Milnacipram.
I have been getting my hormones checked out, and researching various theories like adrenal fatique syndrome. I am considering trying Ablify or Nefazone as well. Ultimately, I don't know what happened. My doctor says it is atypical. I have only found a small handful of people on the internet who have similar experiences.
Of course, if you can do it, a "drug holiday" is probably best.
poster:NewQuestions
thread:867043
URL: http://www.dr-bob.org/babble/20081204/msgs/867476.html