Posted by CaptainAmerica1967 on December 17, 2008, at 20:18:14
In reply to Re: Treatment Resistant (Refractory) Depression, posted by SLS on December 17, 2008, at 10:18:43
"By the way, what treatments are you aware of that you have not yet tried?"
Deep brain stimulation-hopefully it will continue to show promise in treating severe treatment resistant depression and will be approved even though I don't like surgery as there's always a risk.
Other than that, there's not much I haven't tried except some drugs going through clinical trials.
http://neurotransmitter.net/newdrugs.html
or www.clinicaltrials.gov
-CRF antagonistsI'm still really interest in ketamine (NMDA antagonsit), but cannot or will not get off my current meds (was out) in order to be able to participate in the study. http://clinicaltrials.gov/ct2/show/NCT00088699?cond=%22Depression%22&rank=35
Riluzole(an inhibitor of glutamate release)-indicated for ALS, but studies on going like ketamine.
Also meds that increase brain-derived neurotrophic factor (BDNF) as antidepressants and physical exercise increase levels in the brain and those with depression have reduced levels.
Cysteamine bitartrate (Cystagon), an FDA approved med for the treatment nephropathic cystinosis, has been shown to increase BNDF in neuronal tissue, and to stimulate cell growth.
poster:CaptainAmerica1967
thread:868231
URL: http://www.dr-bob.org/babble/20081214/msgs/869339.html