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Re: Switch from Parnate to (TCAs, Cymbalta)?Help ;-) » Phillipa

Posted by Vincent_QC on January 9, 2009, at 23:46:25

In reply to Re: Switch from Parnate to (TCAs, Cymbalta)?Help ;-) » Vincent_QC, posted by Phillipa on January 9, 2009, at 10:59:24

Hi Phillipa ;-)
Well you're right, getting Emsam patch in Canada will be impossible, so I have to forget this option, since it will be the most "pratical" way to be sure I recieve the good amount of drug into my body...too bad I can't try it. I don't think it will be avaible in the Canada one of these day...like the Manerix will never be avaible in the USA ...

My question about Cymbalta was about how it's made inside the pill???...is it small rounds balls like the Effexor-XR or it's just regular powder or it's hard? If it's not rounds balls, maybe I will be able to crush the pills and take it like this...if it's small round balls I will not be able to do this.

For you question, yes I can absorb most of the "regular" version of drugs...all the SSRI's was absorbed but I never answer well to them.

When a drug hit too much all the SE brains, I feel worst than ever...I just think about food, I gain weight, I lost all the small amount of motivation I have and my social anxiety get worse cause I feel just like a "fat" and ugly guy...since I always gain weight on them, so I can't improve my social phobia and I get more anxious because I loose more self-esteem and I feel guilty cause I can't stop eating...that's a big circle that never stop... Ho...I was able to do very strict diet on a SSRI's...but I loosing weight even on a strict diet on a SSRI drug is what I call a miracle...I don't had a gastric by-pass surgery to find myself again in the big wheel of the DIET...and the YO-YO (mean loose 10 pounds, gain 20 pounds after...)...The SSRI's seem to change something in my system and make me just fat, I don't know what to point, but that's a the reality I have to live on them...soi I prefer to don't play in that field again...

I got my gastric by-pass in 2001. Before 2001, I had already tried a lot of AD's...most of them was on the SSRI's class...I gain most of my weight on the Paxil, I was on it from 19yo to 24yo...I was the first patient my Pdoc had at the time and who gain more than 60 pounds in 2 months...He had never see that before...

So you understand why I don't want to gain more weight again...I had this surgery and I don't want to be fat again...Since last october, I gain more than 45 pounds from Lexapro (Cipralex) and it seem that on the Parnate I continue to gain weight, so that's a major issue for me.

For all the extended version or the slow release drugs, it's hard to predict how many percent of the drugs is absorb by my system. I have a small intestine track, only 1 meter on 6-7 meters for a normal person, I eat something and it's out of my body 4 hours after...and it's not even digested...(I don't want to be disgusting...sorry...lol).

So it's why I was asking for the Cymbalta. If I can make it a regular version by crushing the pill and swallow it after, it can be a good try...But if it's made like the effexor-XR with small rounds balls inside I will not be able to do it and try it...

So for now, my only hope will be the Cymbalta (if I can crush it), a TCA's with the fewer side-effects profile, no weight gain as a side-effect if it's possible and the one with the less side effect also on the blood pressure.

The Manerix is also an option, it's seem to be only a milder MAOI's with reversible action. My family doctor always call the Manerix a drug for "cats"...mean that it was not really good and it was for minor problems of depression or social phobia...to be effective he always told me the dose had to be at least 900mg and sometimes 1200mg and at this stage, it act like a irreversible MAOI, so he always said that old MAOI's was more good for treatment resistant patient...

I get a lot tired from the last month experiment on the Parnate and if I have to feel like i'm running a marathon each day of my life just to be relieve of a little bit of my social phobia but not my depression I think I prefer to stay shy and have some social phobia problem than feel like I will pass out everytime...I don't think the ratio of side-effects and improve I see with the Parnate is a good reason to continue the adventure. I deserve at least a minimum of quality of life and I want to be able to keep it... I don't want to wait again 2 months just to see if the side-effects of the Parnate will fade away, i'm not ready to live another 2 months like the one I just had...

Another time, that's just my point of view...Thanks for you support...and if you can tell me how the Cymbalta is made inside, it will help me a lot!!! ;-)

Have a nice weekend ;-)

Bye!

Vincent ;-)


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