Posted by bulldog2 on January 26, 2009, at 17:10:49
In reply to I'm 100% cured of Social Phobia!!!, posted by Medline on January 26, 2009, at 13:16:18
> First of all: Don't try this at home kids! I have year long experience with psychoactive drugs, which I am not really proud of. :-( I've made a lot of mistakes, some of which I could have paid the ultimate price for - my life. Nevertheless giving up wasn't an option for me at any point.
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> SAD involves dysfunction of the Serotonin-, Dopamine-, GABA-, Oxytocin- and probably Norepinephrine-System.
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> Fact: about 30-40% of patients do not adequately respond to a treatment with first line agents (SSRIs/SNRIs). These people might be helped by long term Pregabalin/Clonazepam or MAOI-treatment. But some have to be considered "therapy resistent".
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> Hypothesis: Elevating levels of 5-HT, DA, GABA, NE and Oxytocin in the CNS increases the probability of making a complete recovery. Low dose of the NMDA-antagonist Cycloserine may help to "hardwire" the results in the brain.
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> My regimen:
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> 2 x 300mg Moclobemide / day:
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> Increases levels of Serotonin and Norepinephrine.
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> 2mg Selegiline / day:
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> Works on Dopamine, but leaves enough Monoamine Oxidase so that Tyramine can be broken down and no special diet has to be followed.
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> 4 x 1.5ml of GBL / day:
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> Non-toxic precursor for GHB, legal in my country (but not in the US!). Increases levels of Oxytocin, GHB and probably GABA-B in the CNS. Potent anxiolytic and empathogen.
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> 50mg Baclofen / night:
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> Extremely important! Never take GHB/GBL 24/7 or severe dependence and withdrawal will occur. Baclofen helps with that and you can sleep very well and resftul.
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> 50mg Cycloserine / day:
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> May help to make the results permanent.
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> I take this from Monday-Friday. On weekends I take 2mg Klonopin / day instead of Baclofen and GBL to avoid tolerance and physical dependence.
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> This cocktail completely kills SA and depression. I've tried all Psychodrugs known to man (SSRIs/SNRIs, tricyclic and atypical ADs, MAOIs, Mood stabilizers, Neuroleptics, Alcohol, Benzos, Phenobarbital, Clomethiazole, Buprenorphine) but nothing works as effectively as this regimen.
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> What do you think?Sounds like a potent brew!
I myself use high dose neurontin a couple times a week and it's a great ad and social lubrcant for me. Won't take it everyday as one quickly becomes tolerant to it.
poster:bulldog2
thread:876329
URL: http://www.dr-bob.org/babble/20090104/msgs/876384.html