Posted by myco on February 1, 2009, at 13:15:54
In reply to Re: Unisom-2 (DOXYLAMINE) in CANADA (VINCE) » myco, posted by raisinb on February 1, 2009, at 11:20:06
Hey,
The most common OTC sleep med ingredient, at least in Canada, is diphenhydramine (unisom, nytol, sleepeeze - all same ingredient as benedryl) which is a sedating antihistamine. There is another type of unisom (unisom-2 and unisom 'sleep tabs') that uses doxylamine instead. This is also a sedating antihistamine. Just look on the front of the box of the sleep aid (or the side listing ingredients) to distinguish them. As far as im aware, from the literature, I believe diphenhydramine may have weak seratonin inhibiting abilities making it less desireable for MAOI users compared to doxylamine...although maois will potentiate anticholinergic effects (ie dry mouth) of them both. Ive found doxylamine to work better for sleep actually and less drying than diphenhydramine. Also ya, I agree, I feel abit "slower" the next day after taking diphenhydramine compared to doxylamine. Sleep onset is also faster for doxylamine from my perspective. Both suffer from wearoff in the middle of the night though resulting in my awaking after about 4-5h after dosing. Redosing helps and they are both cheap and OTC so thats fine.
keep smilin,
myco
atypical depression, gad, social anxiety
75mg nardil
poster:myco
thread:875362
URL: http://www.dr-bob.org/babble/20090104/msgs/877525.html