Posted by metric on April 13, 2009, at 17:59:03
In reply to Re: Opinions, posted by linkadge on April 12, 2009, at 20:17:51
> The upregulation of gaba-b may or may not lead to an increased net activation of gaba-b recepors.
>
> Perhaps they are being increased as an inhibitory adaptive responce to the drug.That was my first thought.
To the original poster: as someone who has used both GHB (lots of it) and tranylcypromine (Parnate), the subjective effects are not remotely similar, although both drugs are euphoriants.
If you want a GABA-B agonist, there is always baclofen, which is non-scheduled and thus easy to obtain. Another option is phenibut, which at very high doses seemed weakly reminscent of GHB, although tolerance developed rapidly. Phenibut can be purchased as a "dietary supplement" in the U.S.
poster:metric
thread:890191
URL: http://www.dr-bob.org/babble/20090408/msgs/890409.html