Posted by tensor on May 4, 2009, at 7:51:11
In reply to Re: Edronax + Zoloft not working for MDD » tensor, posted by SLS on May 4, 2009, at 7:25:05
> Well, at least you now know that a drug with NE reuptake inhibition is helpful, for whatever reason. I would just mention that some top clinicians are looking at the utility of mixing SRIs like Zoloft and Effexor with NRIs like reboxetine, desipramine, and nortriptyline.
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> I have a bipolar depression that has shown itself to be very difficult to treat. However, some drugs and drug combinations have had positive impacts. For what it's worth, I experienced a pretty stable mild improvement from combining Effexor with nortriptyline. That a treatment is capable of improving my condition at all is probably a good sign that it will be effective for others. Yes, I think you can go ahead and try to swap-out the Zoloft for another SRI. I recommend either Effexor or Lexapro. Don't be bashful about adding Wellbutrin to either of these two drugs. There's magic in them there pills.
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> - ScottThanks for your reply Scott.
I have always responded best to noradrenergic agents. I tried Effexor about ten years ago, did nothing for my depression and I had horrible night sweating on it, the sheets were completely soaked in sweat when I woke up, and then there are those weird dreams.. Of course I could respond differently to it now. So you think switching from Zoloft to Lexapro could make a difference?
Edronax have worked for me before and I'm disappointed about the lack of response now. Historically it has taken 6-7 months for me to recover from a depression regardless of medication, I'm scared that I have to wait this one out too./Mattias
poster:tensor
thread:894191
URL: http://www.dr-bob.org/babble/20090426/msgs/894197.html