Posted by Chairman_MAO on June 1, 2009, at 5:55:05
I'd be interested to see if any compounding
pharmacy could make e.g. 100mg tranylcypromine
tablets with this stuff. I'd switch to that
in a heartbeat if that were possible (200mg/day).
In general, it seems like this stuff has
potential, and so I just thought I'd mention it:Our lead technology platform, Contramid®, can be applied to a wide variety of drugs in solid, oral dosage form to optimize compliance, safety, bioavailability and performance.
What Is It?
Contramid is a cross-linked, high amylose starch drug delivery technology that meters the release of drugs from orally administered solid dosage forms.
How Does it Work?
In its dry state, Contramid acts as a free flowing, highly compressible powder. When in tablet form and wetted, it forms a long-lasting, uniform surface membrane that is ideally suited to controlled release of orally administered drugs under a broad range of in-body conditions.
What Are Its Advantages?
Contramid has the following advantages as a controlled-release technology:
* High drug loading capacity (important for once-daily formulations);
* Flexible release profiles to maximize efficacy and minimize side effects;
* Ability to release multiple drugs from a single tablet with different release rates;
* Safe: Contramid complies with FDA and EP regulations for modified starches and may be used in any proportion in oral pharmaceuticals. Being starch-based it is also completely biodegradable.What Have We Done With It?
Our once-daily formulation of tramadol, now on the market in Europe, validates our Contramid technology in solid, oral dosage applications. We are currently working to exploit Contramids potential through a number of different presentations.
poster:Chairman_MAO
thread:898744
URL: http://www.dr-bob.org/babble/20090531/msgs/898744.html