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Re: Is 60mg of Remeron a SAFE Dosage? » Phillipa

Posted by yxibow on June 27, 2009, at 23:40:08

In reply to Re: Is 60mg of Remeron a SAFE Dosage? » BRC, posted by Phillipa on June 27, 2009, at 22:00:29

> If it ain't broke don't need fixing. Phillipa

I agree with that, and I also agree with routine blood testing which should be done for polypharmacy if at all possible -- the standard of care is usually every 6 months, but if copays are possible for 3 months, that's even better.

I am curious though about 3 antidepressants -- two of which act on NE, all three of which act in varying degrees and ways on serotonin. I assume your doctor is aware of the dangers of SS (serotonin sysndrome).

And then there are two mood/anxiety stabilizers there but those two combinations are much more common.

Lipitor isn't completely innocuous but its not in the scope of what I'm more concerned with, which is SS.

As for it being a safe dosage ... well I'm probably more of a heavy set and fast metabolizer than you are when I took Remeron... I did go up to 52.5 (7.5 mg tablets). 60mg is probably not much a difference from that but I wouldn't really go too much higher.

Its pretty groggy making for at least the first while anyhow.

More isn't always better (I went to 120 Cymbalta when I took it, and it wasn't clear, nor did the drug company have any evidence that 120 was any better than 60, but it probably did a bit more for me.)

Cymbalta ha around a 6:1 serotonin to NE ratio so its lower acting if I recall on NE than it is on serotonin.

Good luck and just monitor your mood and state of mind occasionally -- SS though is really hard to pin down because the patient doesn't actually often know they have it.

I suppose anything I say could be processed/construed as a warning, but I'm not trying to upset the balance of your medications nor is that my intention to scare someone.

If they've been working fine, average monitoring by your doctor should be sufficient enough.

-- tidings

Jay

 

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