Posted by uncouth on August 28, 2009, at 21:21:35
In reply to AD that will get me out of bed, posted by morganator on August 27, 2009, at 0:21:58
only thing i have to add is, do not underestimate the adaptive changes that take place when you are on an MAOI for a meaningful amount of time. an MAOI is a huge shock to the system and the brain "grows" around the drug. all of a sudden allowing MAO to come back and do it's job, while thinking that an SNRI will be enough to "pick up the slack" is crazy in my opinion.
I have been on Emsam and Parnate for a total of 9 months. I wasn't doing that great on Parnate, and wanted to switch to Effexor+Adderall. That was the decision that ended up putting me in the hospital, 22 sessions of ECT, and a merrygoround of meds i'm on right now that we still can't get right. Now i'm on Wellbutrin 450. What I should have done is not gone off the parnate, but gone UP, and added Lithium and Abilify.
MAOIs are extremely powerful and effective when dosed correctly but they do cause serious changes to brain physiology.
poster:uncouth
thread:914302
URL: http://www.dr-bob.org/babble/20090826/msgs/914596.html