Posted by bleauberry on November 21, 2009, at 14:41:02
In reply to in theory could this work, posted by manic666 on November 21, 2009, at 7:52:37
I would feel fairly confident in combining the lowest dose of cymbalta with a moderate dose of zoloft without risk of serotonin syndrome. But there is no way to predict.
However there are much better options. For example, as a pain reliever, Nortriptyline in my experience blows cymbalta in the weeds. I haven't tried amitriptyline, but I suppose it would work as well or better than nortriptyline.
I've tried a lot of pain relievers for Lyme disease complications. The best of the best was a mere 5mg (one half of the lowest dose capsule) nortriptyline nightly. The pains began disappearing by day 3 and were gone by day 5. I liked that it worked so fast and so thorough at such a low dose with hardly any side effects at that dose.
I'm not a rocket scientist or a doctor but I do not favor cymbalta. A few people find it to be miraculous once in a while, but those stories usually end in poopout a few months later. For me it is also a depression worsener, not a depression improver. If someone has issues of depression and pain, in my book the number one first line trial is nortriptyline, maybe amitriptyline instead if insomnia is also an issue.
Nortriptyline also happens to partner very well with zoloft for a more thorough antidepressant response.
My two cents.
poster:bleauberry
thread:926414
URL: http://www.dr-bob.org/babble/20091117/msgs/926444.html