Posted by mtdewcmu on November 24, 2009, at 22:39:35
In reply to Re: I'm taking Abilify » mtdewcmu, posted by jparsell82 on November 24, 2009, at 21:54:35
> > > I just came across this study the other day:
> > >
> > > http://www.ncbi.nlm.nih.gov/pubmed/17455104
> > >
> > > Shows Abilify helps counteract the weight gain of Remeron and Remeron helps counteract the akathisia of Abilify.
> > >
> > > I'm curious as to how this combo feels. I've gotten benefit from Abilify before(2mg) but got bad akathisia from it. I wonder if Remeron would completely relieve the akathisia and I also wonder if the Abilify would do anything for the daytime sedation caused by Remeron... interesting combo.
> >
> > I am curious to know what part of Remeron's effect was beneficial for akathisia. I have a feeling it may just have been the sedation caused by the histamine blockade. However, if it turns out that Remeron is a universal antidote for akathisia, that would be very useful. I could not tolerate 150mg of Zoloft due to akathisia-like side effects; I wonder if I would be able to tolerate that amount in combination with Remeron.
>
> "Marked 5HT2A/2C antagonistic activity of mirtazapine apparently accounts for its anti-NIA activity"
>
> That's quoted from the study I posted previously... nia stands for neuroleptic induced akathisia.I guess it may be worth trying 150mg of Zoloft again. I think I'd like to try increasing the Remeron first, however. I don't know why my doc only prescribed 15mg. I am afraid that the antidepressant effect I am feeling from my meds right now is too weak, and I think I may still have some headroom with this combination.
poster:mtdewcmu
thread:925843
URL: http://www.dr-bob.org/babble/20091117/msgs/926900.html