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Re: thankyouthankyouthankyou!

Posted by SLS on November 29, 2009, at 7:11:31

In reply to Re: thankyouthankyouthankyou!, posted by morganator on November 28, 2009, at 22:43:41

> http://www.google.com/url?sa=t&source=web&ct=res&cd=3&ved=0CA4QFjAC&url=http%3A%2F%2Fclinpsyc.blogspot.com%2F2008%2F09%2Fbig-drugs-small-brains.html&ei=h_sRS-K0Gc2_lAfo27icBA&usg=AFQjCNGpTSS6Fj1MGXr9TTFDp3C2R6b8aQ&sig2=KA4ZwIi1UubOy3YmFhNf-A

I'm not sure that sharing an anti-psychiatry blog is the way to go. However, I do appreciate the citation they offer to the macaque study.

The only research on Medline that I could find that reports reduced brain tissue in lab animals treated with antipsychotics has been performed by the same research team from the University of Pittsburgh. Their published papers on this issue first appeared in 2005. I am surprised that no follow-up studies have been conducted by others to replicate the results. Maybe there just isn't enough interest. Of course, this, too, is scary. In general, I find the work of the research team to be sophisticated and respectable. However, it would be nice to see it replicated should they be wrong.

I did find an interesting study that reported a normalization of myelination in subjects with schizophrenia when atypical, but not typical, antipsychotics are used. This indicates an increase in white matter volume.

http://www.ncbi.nlm.nih.gov/pubmed/19616412?


- Scott

 

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