Posted by SLS on December 15, 2009, at 11:39:33
In reply to Combining Nortriptyline and Parnate, posted by inanimate peanut on December 15, 2009, at 10:12:08
> Everything I'm reading says you can't combine Nortriptyline (or any TCA) and Parnate (or any MAOI). Who here is doing it and are there any problems with it?
I came across a great review article last week describing the safe use of a combination of a MAOI and a TCA. I can't find it now.
I have mixed and matched either Parnate or Nardil with desipramine and nortriptyline. I have also come upon people who have used doxepin and amitriptyline with a MAOI. However, imipramine and clomipramine should not be used with MAOIs because they are too potent as serotonin reuptake inhibitors. Serotonin syndrome is the concern here.
Problems that arise during combination treatment include hypotension and urinary hesitancy. These are usually manageable, though, and can mitigate over time to some extent.
- Scott
poster:SLS
thread:929389
URL: http://www.dr-bob.org/babble/20091206/msgs/929396.html