Posted by Ron Hill on December 30, 2009, at 4:41:58
In reply to Re: How come more of you are on parnate than nardil? » Ron Hill, posted by jedi on December 30, 2009, at 4:06:43
Jedi,
I think I'm going to add topiramate (Topamax) due to it's weight loss effect. Further, some studies indicate that topiramate can treat bipolar depression and rapid cycling.
However, Topamax has a lot of possible side effects, one of which is depression.
Has Nardil caused weight gain for you?
-- Ron
-----------------> Hi Ron,
> Our stories are similar. Nardil knocked out my first major depression over 12 years ago. It was like flipping a switch when it worked. The side effect profile caused me to quit the medication multiple times for other drug trials, including two on Parnate. Out of 45+ different combinations nothing has worked for my atypical depression and social anxiety except phenelzine combined with clonazepam. Both of these meds affect GABA. I have reduced my Nardil from 90mg to 60mg to lower the side effect profile. As it stands now, I'm a lifer on Nardil.
>
> For atypical depression and social anxiety, you will not find a better combination than phenelzine + clonazepam(IMHO). Of course, with the benzodiazepine, don't count on being able to remember what you had for lunch. There are always trade offs.
> Good Luck,
> Jedi
>
> > > I mean has anyone had separate trials of nardil and of parnate, not taken at the same time
> > ---------------
> >
> > Julie,
> >
> > I started taking Nardil in the spring of 2006 and continually took it until the spring of 2009 at which point I washed out Nardil and started Parnate. I liked Nardil a lot, but the 50 pound weight gain, ED, and anorgasam caused me to try switching to Parnate.
> >
> > But, Parnate did not provide any antidepressant action for me. I gave the Parnate trial four months, and I was severely depressed throughout the entire trial. It was hell. So, I washed out the Parnate and restarted Nardil. As soon as I restarted Nardil, my depression reduced to pre-Parnate trial levels.
> >
> > I am a bipolar II with ultra rapid cycling; 15 day cycle, nine days of full remission, followed by six days of depression. This is my cycle on Nardil. On Parnate, I was always severely depressed.
> >
> > I take 90 mg/day of Nardil. During my Parnate trial, I ramped up very quickly to 80 mg/day. Perhaps I should have increased to 120 mg/day or higher of Parnate before discontinuing the trial.
> >
> > -- Ron
> >
> >
> > dx: Bipolar II with ultra rapid cycling and mild OCPD
> >
> > 600 mg/day Trileptal
> > 200 mg/day Lamictal
> > 500 mg/day Keppra
> > 90 mg/day Nardil
> > 1.9 mg/day Deplin (taken with methyl B-12 and P-5-P)
> > Dark therapy via LowBlueLight glasses
> > Exercise: Ride, Lift, Swim, and Sauna
> > Several vitamins and supplements
> >
>
>
poster:Ron Hill
thread:931242
URL: http://www.dr-bob.org/babble/20091227/msgs/931544.html