Posted by mtdewcmu on January 2, 2010, at 13:23:05
In reply to Re: An AD that affects serotonin besides an SSRI » West, posted by SLS on December 30, 2009, at 13:13:25
> > Can you substantiate this claim?..."(adding a tricyclic to an SSRI)
>
> I don't know about the side effect thing, but for me, I find that a combination of Effexor and nortriptyline produces a more robust antidepressant effect than either drug alone.
>
> I found that I needed full therapeutic dosages of both drugs when they were combined. The presence of one drug did not reduce the minimum effective dosage of the other.
>
>
> - ScottThe more the merrier. It seems to me that a tricyclic could be a useful way to add a norepinephrine effect. I may wind up adding one to my own regimen.
I also wonder if the central anticholinergic property has a slight mood-elevating effect. Apparently Artane is a drug of abuse in some parts of the world.
poster:mtdewcmu
thread:931322
URL: http://www.dr-bob.org/babble/20091227/msgs/932130.html