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Re: SSRI's + extra pyramidal s/e's

Posted by linkadge on February 1, 2010, at 6:52:34

In reply to SSRI's + extra pyramidal s/e's, posted by g_g_g_unit on February 1, 2010, at 0:39:30

Theoretically, zoloft would be better, but I've never seen data to support this.

>is the only real solution augmenting with >parkinson's drugs?

This side effect may be more pronounced in people with 'low dopamine' to begin with. You may try a lesser dose of the SSRI. You might augment with something like mirtazapine (or cyproheptadine / low dose TCA) (which blocks inhibitory serotonin receptors). Bupropion augmentation might offset this effect. You might also get relief with a benzodiazapine.

Another option is to switch to a TCA, mirtazapine or bupropion.

A stimulant may help, but it may end up depleting dopamine more in the long run. An agent like coenzyme q10 might be beneficial as it has the ability to ameleorate drug induced catecholamine disturbances.

Other options include tyrosine, caffiene or a dopamine agonist.

Linkadge


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