Posted by casse on February 5, 2010, at 17:07:58
In reply to Re: Are These Meds For Real? Ad's???? Stablon, posted by Ernie D. on January 28, 2010, at 16:34:21
Hi Ernie,
I felt a difference almost immediately. I was experiencing some pretty distressing physical symptoms, wheezing, diarrhea, abdominal pain and cramping, and the Stablon helped within minutes of the first doze of half a 12.5mg tablet.
I have been using the generic tianeptine (Tynept) for almost 5 weeks and still feel much better on it than I did before. I do have breakthrough symptoms if I forget to take my next dose within 6 hours though. I am currently taking 12.5 mg. three times daily.
Here is some information about drug interactions I got with my last order. It contains some information I had not seen on any of the websites and I think it's important to know.
Casse
WARNING: YOU MUST CONSULT YOUR DOCTOR BEFORE USING ANY MEDICATION.
Interactions between your selected drugs
trazodone ⇔ Tianeptine
Applies to: trazodone, Stablon (Tianeptine)
MONITOR CLOSELY: Concomitant use of agents with serotonergic activity such as serotonin reuptake inhibitors, monoamine oxidase inhibitors, tricyclic antidepressants, 5-HT1 receptor agonists, ergot alkaloids, lithium, St. John's wort, phenylpiperidine opioids, dextromethorphan, and tryptophan may potentiate the risk of serotonin syndrome, which is a rare but serious and potentially fatal condition thought to result from hyperstimulation of brainstem 5-HT1A and 2A receptors. Symptoms of the serotonin syndrome may include mental status changes such as irritability, altered consciousness, confusion, hallucinations, and coma; autonomic dysfunction such as tachycardia, hyperthermia, diaphoresis, shivering, blood pressure lability, and mydriasis; neuromuscular abnormalities such as hyperreflexia, myoclonus, tremor, rigidity, and ataxia; and gastrointestinal symptoms such as abdominal cramping, nausea, vomiting, and diarrhea.MANAGEMENT: In general, the concomitant use of multiple serotonergic agents should be avoided if possible, or otherwise approached with caution if potential benefit is deemed to outweigh the risk. Patients should be closely monitored for symptoms of the serotonin syndrome during treatment. Particular caution is advised when increasing the dosages of these agents. The potential risk for serotonin syndrome should be considered even when administering serotonergic agents sequentially, as some agents may demonstrate a prolonged elimination half-life. For example, a 5-week washout period is recommended following use of fluoxetine before administering another serotonergic agent. If serotonin syndrome develops or is suspected during the course of therapy, all serotonergic agents should be discontinued immediately and supportive care rendered as necessary. Moderately ill patients may also benefit from the administration of a serotonin antagonist (e.g., cyproheptadine, chlorpromazine). Severe cases should be managed under consultation with a toxicologist and may require sedation, neuromuscular paralysis, intubation, and mechanical ventilation in addition to the other measures.
poster:casse
thread:931139
URL: http://www.dr-bob.org/babble/20100204/msgs/936060.html